Spoken English

Is spoken English different to written English?
Do native speakers use the same conectors when they speak and when they write?
Shall we use "firstly, secondly, furthermore", or are they are more formal markers?

What about "at the end of the day, basically

the reality is, for me, as I said, I’m aware of, let me give you an example. Do you think they sound more, like "spoken English? 
 Clik here if you want to read about some key differences between the  spoken and written language.